A New Discovery
in Every Chip
At INITIO CELL, we develop patented
multi-functional organ-on-a-chip devices and
assays for drug discovery and diagnostics.
Classical drug discovery uses 2D cell culture coupled with animal testing for preclinical studies. Neither 2D cell culture nor animal testing truly recapitulate the in vivo micro environments of cells in a human body. The paradigm shift is to use 3D cell culture in organ-on-a- chip devices that can faithfully mimic the in vivo conditions. Using organ-on- chip technology is expected to reduce R&D costs (186 B $ in 2020) by 26%.
Distance Dependent Interaction DDI-Chip
The DDI-Chip investigates the interactions between cells and cells and/or factors at different distances from each other in a physiological setup and allows simultaneous investigation of different distances in the same device.
Invasion Chemotaxis IC-Chip Flow
IC-chip Flow provides an easy-to-use and physiologically relevant microenvironment to directly visualize and quantitatively assess effects of flow with high temporal and spatial resolution.
Invasion Chemotaxis IC-Chip
IC-chip provides an easy-to-use and physiologically relevant microenvironment to directly visualize and quantitatively assess migration and invasion of cells with high temporal and spatial resolution. IC-chip also provides the main platform for mimicking various organs such as lung, gut, skin and brain with or without vasculature.
IC-Chip Organoid provides an easy-to-use and physiologically relevant microenvironment to directly visualize and quantitatively assess organoid biology with high temporal and spatial resolution. Also available in flow format.
Initio Cell provides organ-on-chip devices and assays for invasion/chemotaxis, distance dependent cell-cell interactions, extravasation and homing choices of cancer cells.
Initio Cell organ-on-chip devices can be used to create microenvironments of the tumor, lung, gut, skin, brain and vasculature.
Initio Cell provides organ-on-chip devices in both PDMS-glass and PC formats.
Initio Cell organ-on-chip devices can be used with any cell type (including microorganisms), organoids, biopsy samples and virtually all hydrogels so that the users are free to define the specific conditions for their experiments.
Initio Cell organ-on-chip devices can be loaded with standard pipet tips and micropipets.
Initio Cell organ-on-chip devices can be imaged using optical, fluorescent and confocal microscopes in real time or at specific time points.
is enabling the transformation of pharmaceutical industry today.
Clinical symptoms and lately biomarkers are used for diagnostics of cancer among other diseases. However, functional assays at the cellular level where cellular phenotypes can be directly determined are lacking. Organ-on-chip devices that successfully mimic the in vivo conditions can enable functional cellular phenotyping and thus realize precision medicine in the true sense.